New preclinical findings highlight Telomir-1’s ability to reverse CDKN2A gene silencing by DNA methylation, reactivating this gene – often called the body’s natural “cell cycle brake.” These results ...
New in vitro results show Telomir-1 adds KDM5 family inhibition to its previously reported KDM2/KDM6 and DNA methylation ...
New research from Dana-Farber Cancer Institute shows that a new class of drug results in cell death in cancers, such as small cell lung cancer, with a disabled quality control cell cycle checkpoint ...
Cancer treatment is about more than just tumors, genetics, and chemotherapy, it turns out the trillions of microbes living in ...
Cancer cells are pretty bold and clever—they hijack cellular survival and healing processes in order to fuel their growth, ...
An enhanced computer model is now helping to provide fresh insights into cancer-cell growth and how it can be stopped. The digital cell model represents another step towards individualized cancer ...
Circle Pharma, Inc., a clinical-stage biopharmaceutical company pioneering next-generation targeted macrocycle therapeutics for cancer, today announced an upcoming poster presentation highlighting the ...
Avenzo Therapeutics Initiates Phase 1/2 Clinical Study of AVZO-103, a Potential Best-in-Class Nectin4/TROP2 Bispecific ADC ...
In tissue biopsies, cancer cells are frequently observed to have nuclei (the cell's genetic information storage) that are larger than normal. Until now, this was considered a sign that the cancer was ...
A recent study published in the journal Frontiers in Endocrinology investigated the role of the short-chain dehydrogenase/reductase 42E member 1 (SDR42E1) enzyme in regulating sterol metabolism and ...
Before a chain of amino acids can become an active and useful protein, it must be processed and folded into the appropriate ...