Mondolfo is a comune in the Province of Pesaro e Urbino in the Italian region Marche, located about 35 kilometres northwest of Ancona an…Mondolfo is a comune in the Province of Pesaro e Urbino in the Italian region Marche, located about 35 kilometres northwest of Ancona and about 25 kilometres southeast of Pesaro, on the Adriatic Sea. Mondolfo borders the following municipalities: Castel Colonna, Fano, San Costanzo, Senigallia, Trecastelli. It is one of I Borghi più belli d'Italia.